Green fluorescent protein-based lactate and pyruvate indicators suitable for biochemical assays and live cell imaging
Glycolysis is the metabolic pathway that converts glucose into pyruvate, whereas fermentation can then produce lactate from pyruvate. Here, we developed single fluorescent protein (FP)-based lactate and pyruvate indicators with low EC50 for hint detection of metabolic molecules and live cell imaging and named them “Green Lindoblum” and “Green Pegassos,” respectively.
Green Lindoblum (EC50 of 30 µM for lactate) and Green Pegassos (EC50 of 70 µM for pyruvate) produced a 5.2- and 3.3-fold change in fluorescence depth in response to lactate and pyruvate, respectively. Green Lindoblum measured lactate ranges in mouse plasma, and Green Pegassos together with D-serine dehydratase efficiently estimated D-serine ranges launched from mouse main cultured neurons and astrocytes by measuring pyruvate degree.
Furthermore, live cell imaging evaluation revealed their utility for dual-colour imaging, and the interaction between lactate, pyruvate, and Ca2+ in human induced pluripotent stem cell-derived cardiomyocytes. Therefore, Green Lindoblum and Green Pegassos might be helpful instruments that detect particular molecules in scientific use and monitor the interaction of metabolites and different associated molecules in various cell varieties.
Promoter Pull-Down Assay: A Biochemical Screen for DNA-Binding Proteins
Transcription components are ubiquitous proteins that affiliate with promoter DNA and regulate gene expression by way of quite a lot of mechanisms. Understanding transcriptional management mechanisms requires in-depth investigation of the binding of transcription components to the promoters they regulate.
There are many in vivo and in vitro strategies for testing the binding of a identified protein to a promoter, reminiscent of chromatin immunoprecipitation and electrophoretic mobility shift assays. However, for these experiments, one will need to have a protein candidate to check and is just not capable of determine unknown proteins sure to a selected promoter.
Thus, the promoter pull-down assay was developed to fill this void. This technique makes use of DNA as bait to seize proteins that bind to a particular promoter, reminiscent of transcription components, from mobile lysates. Coupled with different experiments, the promoter pull-down assay vastly improves the repertoire of strategies obtainable for defining regulatory complexes that affect transcription.
Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay
Inappropriate activation of endosomal TLR7 and TLR8 happens in a number of autoimmune illnesses, particularly systemic lupus erythematosus (SLE). Herein, the event of a TLR8 antagonist competitors assay and its software for hit era of twin TLR7/Eight antagonists are reported.
The structure-guided optimization of the pyridone hit <b>3</b> utilizing this biochemical assay together with mobile and TLR8 cocrystal structural information resulted within the identification of a extremely potent and selective TLR7/Eight antagonist (<b>27</b>) with <i>in vivo</i> efficacy.
The two key steps for optimization have been (i) a core morph guided by a TLR7 sequence alignment to attain a twin TLR7/Eight antagonism profile and (ii) introduction of a fluorine within the piperidine ring to scale back its basicity, leading to enticing oral pharmacokinetic (PK) properties and improved TLR8 binding affinity.
Hunting monolignol transporters: membrane proteomics and biochemical transport assays with membrane vesicles of Norway spruce
Monolignol transport throughout lignification is {a partially} solved puzzle: each the mechanism(s) and the transported type of monolignols are unknown in creating xylem of timber. We examined a speculation of an energetic, plasma membrane (PM)-localized transport of monolignol monomers, dimers, and/or glucosidic types with membrane vesicles ready of creating xylem and lignin-forming tissue-cultured cells of Norway spruce (Picea abies L. Karst.), in addition to of management supplies, non-lignifying Norway spruce phloem and tobacco (Nicotiana tabacum L.) BY-2 cells. Xylem and BY-2 vesicles transported each coniferin and p-coumaryl alcohol glucoside, however inhibitor assays prompt this transport being over the tonoplast.
Also membrane vesicles ready from the lignin-forming spruce cells confirmed coniferin transport, however the Km for coniferin was a lot increased than these of xylem and BY-2 cells. Liquid chromatography-mass spectrometry (LC-MS/MS) evaluation of membrane proteins remoted from spruce creating xylem, phloem and lignin-forming cultured cells revealed a number of transporters.
These have been in comparison with a transporter gene set that was gained by a correlation evaluation with a particular set of spruce monolignol biosynthesis genes. Biochemical membrane vesicle assays confirmed no help for the ABC-transporter-mediated monolignol transport however level to secondary energetic transporters (reminiscent of MFS or MATE transporters). In distinction, proteomic and co-expression analyses counsel a job for ABC transporters and MFS transporters.
Protective Mechanism of Acacia saligna Butanol Extract and Its Nano-Formulations in opposition to Ulcerative Colitis in Rats as Revealed by way of Biochemical and Metabolomic Assays
Ulcerative colitis (UC) is a relapsing inflammatory illness of unknown etiology. The elevated danger of most cancers in UC sufferers warrants for the event of novel drug remedies. Herein, this work issues with the investigation of the protecting results of Acacia saligna butanol extract (ASBE) and its nanoformulations on UC in a rat mannequin and its underlying mechanism. Colitis was induced by gradual intrarectal infusion of two mL of 4% (v/v in 0.9% saline) acetic acid. Colon samples have been evaluated macroscopically, microscopically, and assayed for pro-inflammatory cytokine ranges.
To monitor related metabolic adjustments in acetic acid-induced UC mannequin, serum samples have been analyzed for main metabolites utilizing GC-MS adopted by multivariate information analyses. Treatment with ASBE attenuated acetic acid-induced UC as revealed by discount of colon weight, ulcer space, and ulcer index.
ASBE remedy additionally decreased Cyclooxygenase-2 (COX-2), Prostaglandin E2 (PGE2) & Interleukin-1β (IL-1β) ranges within the infected colon. The nano-formulation of ASBE confirmed higher safety than the crude extract in opposition to ulcer indices, elevated PGE2 manufacturing, and histopathological alterations reminiscent of intestinal mucosal lesions and inflammatory infiltration.
Distinct metabolite adjustments have been recorded in colitis rats together with a lower in oleamide and arachidonic acid together with elevated ranges of lactic acid, fructose, and pyroglutamic acid.
 Sheep BACE1 ELISA Kit |
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| ESB0322 | Abclonal | 96Tests | 625.2 EUR |
 Human BACE1 ELISA Kit |
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| ELA-E0718h | Lifescience Market | 96 Tests | 988.8 EUR |
 BACE1 ELISA KIT|Human |
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| EF006629 | Lifescience Market | 96 Tests | 826.8 EUR |
Human BACE1 ELISA Kit |
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| EHB0322 | Abclonal | 96Tests | 625.2 EUR |
 Mouse BACE1 ELISA Kit |
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| IMSBACE1KT | Innovative research | each | 548 EUR |
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Description: Mouse BACE1 ELISA Kit |
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Human BACE1 ELISA Kit |
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| IHUBACE1KT | Innovative research | each | 548 EUR |
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Description: Human BACE1 ELISA Kit |
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 Monkey BACE1 ELISA Kit |
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| EMKB0322 | Abclonal | 96Tests | 625.2 EUR |
 Rabbit BACE1 ELISA Kit |
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| ERTB0322 | Abclonal | 96Tests | 625.2 EUR |
 Bovine BACE1 ELISA Kit |
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| EBB0322 | Abclonal | 96Tests | 625.2 EUR |
 Canine BACE1 ELISA Kit |
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| ECB0322 | Abclonal | 96Tests | 625.2 EUR |
 Porcine BACE1 ELISA Kit |
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| EPB0322 | Abclonal | 96Tests | 625.2 EUR |
 Chicken BACE1 ELISA Kit |
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| ECKB0322 | Abclonal | 96Tests | 625.2 EUR |
 Anserini bACE1 ELISA Kit |
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| EAB0322 | Abclonal | 96Tests | 625.2 EUR |
 Guinea Pig BACE1 ELISA Kit |
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| EGB0322 | Abclonal | 96Tests | 625.2 EUR |
 (OKCD02313)) BACE1 ELISA Kit (Rat) (OKCD02313) |
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| OKCD02313 | Aviva Systems Biology | 96 Wells | 981.6 EUR |
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Description: Description of target: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.7 pg/mL |
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 (OKAN05558)) BACE1 ELISA Kit (Human) (OKAN05558) |
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| OKAN05558 | Aviva Systems Biology | 96 Wells | 950.4 EUR |
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Description: Description of target: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.11 ng/mL |
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 (OKAN05559)) BACE1 ELISA Kit (Mouse) (OKAN05559) |
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| OKAN05559 | Aviva Systems Biology | 96 Wells | 950.4 EUR |
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Description: Description of target: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality.;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 14.1 pg/mL |
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 (OKCD06723)) BACE1 ELISA Kit (Human) (OKCD06723) |
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| OKCD06723 | Aviva Systems Biology | 96 Wells | 903.6 EUR |
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Description: Description of target: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.11ng/mL |
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 (OKCD06724)) BACE1 ELISA Kit (Mouse) (OKCD06724) |
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| OKCD06724 | Aviva Systems Biology | 96 Wells | 934.8 EUR |
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Description: Description of target: Bace1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Bace1 cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 12.1pg/mL |
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 (OKEH03206)) BACE1 ELISA Kit (Mouse) (OKEH03206) |
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| OKEH03206 | Aviva Systems Biology | 96 Wells | 794.4 EUR |
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Description: Description of target: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.39 ng/mL |
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 BACE1 |
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| RA21010 | Neuromics | 50 ug | 522 EUR |
BACE1 |
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| E8RT1066 | EnoGene | 100ul | 275 EUR |
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Description: Available in various conjugation types. |
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BACE1 |
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| enz-1119 | ProSpec Tany | 10µg | 60 EUR |
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Description: Recombinant Human Beta-Secretase 1 |
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 Mouse Beta- secretase 1, Bace1 ELISA KIT |
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| ELI-02502m | Lifescience Market | 96 Tests | 1038 EUR |
 Human Beta- secretase 1, BACE1 ELISA KIT |
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| ELI-02503h | Lifescience Market | 96 Tests | 988.8 EUR |
 : 96 Wells (OKEH00554)) BACE1 ELISA Kit (Human) : 96 Wells (OKEH00554) |
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| OKEH00554 | Aviva Systems Biology | 96 Wells | 794.4 EUR |
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Description: Description of target: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015];Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.31 ng/mL |
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 Bovine Beta- secretase 1, BACE1 ELISA KIT |
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| ELI-02504b | Lifescience Market | 96 Tests | 1113.6 EUR |
 Bace1 ELISA Kit| Mouse Beta-secretase 1 ELISA Kit |
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| EF013095 | Lifescience Market | 96 Tests | 826.8 EUR |
 Rat Bace1/ Beta-secretase 1 ELISA Kit |
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| E0115Ra | Sunlong | 1 Kit | 685.2 EUR |
 Human BACE1/ Beta-secretase 1 ELISA Kit |
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| E0249Hu | Sunlong | 1 Kit | 685.2 EUR |
 Mouse Bace1/ Beta-secretase 1 ELISA Kit |
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| E0159Mo | Sunlong | 1 Kit | 685.2 EUR |
 ELISA Kit) Mouse Bace1(Beta-secretase 1) ELISA Kit |
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| EM0448 | FN Test | 96T | 628.92 EUR |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
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 bACE1 siRNA |
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| 20-abx908826 | Abbexa |
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bACE1 siRNA |
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| 20-abx908827 | Abbexa |
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bACE1 siRNA |
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| 20-abx900582 | Abbexa |
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 BACE1 protein |
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| E62B011 | EnoGene | 20ug | 411.6 EUR |
 BACE1 antibody |
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| 20R-BR014 | Fitzgerald | 50 ug | 787.2 EUR |
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Description: Rabbit polyclonal BACE1 antibody |
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BACE1 antibody |
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| 20R-BR015 | Fitzgerald | 50 ug | 787.2 EUR |
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Description: Rabbit polyclonal BACE1 antibody |
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 Bace1 antibody |
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| 70R-8662 | Fitzgerald | 50 ug | 560.4 EUR |
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Description: Affinity purified rabbit polyclonal Bace1 antibody |
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 BACE1 Antibody |
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| 6651-100 | Biovision | each | 418.8 EUR |
BACE1 Antibody |
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| 6651-30T | Biovision | each | 175.2 EUR |
BACE1 antibody |
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| 70R-15953 | Fitzgerald | 50 ul | 522 EUR |
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Description: Rabbit polyclonal BACE1 antibody |
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BACE1 antibody |
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| 70R-7276 | Fitzgerald | 50 ug | 560.4 EUR |
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Description: Rabbit polyclonal BACE1 antibody raised against the N terminal of BACE1 |
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BACE1 Antibody |
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| 35650-100ul | SAB | 100ul | 302.4 EUR |
BACE1 Antibody |
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| ABD7939 | Lifescience Market | 100 ug | 525.6 EUR |
BACE1 Antibody |
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| ABD7999 | Lifescience Market | 100 ug | 525.6 EUR |
BACE1 Antibody |
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| 1-CSB-PA150463 | Cusabio |
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Description: A polyclonal antibody against BACE1. Recognizes BACE1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:2000-1:5000, WB:1:500-1:2000 |
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BACE1 Antibody |
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| 1-CSB-PA173556 | Cusabio |
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Description: A polyclonal antibody against BACE1. Recognizes BACE1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:15-1:50 |
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BACE1 Antibody |
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| 1-CSB-PA008418 | Cusabio |
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|
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Description: A polyclonal antibody against BACE1. Recognizes BACE1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000 |
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BACE1 Antibody |
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| 1-CSB-PA002524GA01HU | Cusabio |
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|
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Description: A polyclonal antibody against BACE1. Recognizes BACE1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
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BACE1 Antibody |
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| 1-CSB-PA002524LA01HU | Cusabio |
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Description: A polyclonal antibody against BACE1. Recognizes BACE1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
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BACE1 Antibody |
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| F50757-0.08ML | NSJ Bioreagents | 0.08 ml | 140.25 EUR |
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Description: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. |
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BACE1 Antibody |
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| F50758-0.08ML | NSJ Bioreagents | 0.08 ml | 140.25 EUR |
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Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt] |
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BACE1 Antibody |
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| F50758-0.4ML | NSJ Bioreagents | 0.4 ml | 322.15 EUR |
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Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. [UniProt] |
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BACE1 Antibody |
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| E307287 | EnoGene | 100ug/200ul | 275 EUR |
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Description: Available in various conjugation types. |
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BACE1 Antibody |
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| DF7939 | Affinity Biosciences | 100ul | 280 EUR |
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Description: Human |
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BACE1 Antibody |
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| AF6650-100ul | Affinity Biosciences | 100ul | 280 EUR |
BACE1 Antibody |
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| AF6650-200ul | Affinity Biosciences | 200ul | 350 EUR |
BACE1 Antibody |
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| AF6650 | Affinity Biosciences | 100ul | 280 EUR |
|
Description: Human,Mouse,Rat |
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BACE1 Antibody |
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| DF7939-100ul | Affinity Biosciences | 100ul | 280 EUR |
BACE1 Antibody |
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| DF7939-200ul | Affinity Biosciences | 200ul | 350 EUR |
BACE1 Antibody |
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| E10-30625 | EnoGene | 100ul | 225 EUR |
|
Description: Available in various conjugation types. |
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BACE1 Antibody |
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| E10-30625T | EnoGene | 100ul | 225 EUR |
|
Description: Available in various conjugation types. |
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BACE1 Antibody |
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| E035650 | EnoGene | 100μg/100μl | 255 EUR |
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Description: Available in various conjugation types. |
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BACE1 Antibody |
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| E19-7939-1 | EnoGene | 50ug/50ul | 145 EUR |
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Description: Available in various conjugation types. |
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BACE1 Antibody |
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| E19-7939-2 | EnoGene | 100ug/100ul | 225 EUR |
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Description: Available in various conjugation types. |
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BACE1 antibody |
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| E39-10412 | EnoGene | 100ug/100ul | 225 EUR |
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Description: Available in various conjugation types. |
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BACE1 Antibody |
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| E305133 | EnoGene | 100ug/200ul | 275 EUR |
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Description: Available in various conjugation types. |
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 BACE1 Assay Kit |
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| 71656 | BPS Bioscience | 96 rxns. | 530 EUR |
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Description: Bace1 (β-secretase 1) is an aspartic protease that is involved in the processing of the Amyloid precursor protein (APP). Cleavage of APP by BACE1 followed by γ-secretase results in β-amyloid peptide production, which ultimately leads toxic Aβ accumulation. In Alzheimer's disease (AD), it has been widely accepted that Aβ aggregation plays a critical role in AD pathogenesis, suggesting that BACE1 could be a potential target to treat AD. The BACE1 FRET Assay Kit is designed to measure BACE1 activity for screening and profiling applications based on fluorescence resonance energy transfer (FRET) using a labeled peptide substrate (below). |
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 BACE1 ELISA Kit| Rat Beta Site APP Cleaving Enzyme 1 ELISA Kit |
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| EF017555 | Lifescience Market | 96 Tests | 826.8 EUR |
 ELISA Kit) Rat Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx256725-96tests | Abbexa | 96 tests | 801.6 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| 20-abx155244 | Abbexa |
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 ELISA Kit) Cow Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx513826-96tests | Abbexa | 96 tests | 1093.2 EUR |
 ELISA Kit) Pig Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx361238-96tests | Abbexa | 96 tests | 990 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx353523-96tests | Abbexa | 96 tests | 801.6 EUR |
 Human β-site APP-Cleaving Enzyme 1, BACE1 ELISA kit |
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| CSB-E09824h-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
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Description: Quantitativesandwich ELISA kit for measuring Human β-site APP-Cleaving Enzyme 1, BACE1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human β-site APP-Cleaving Enzyme 1, BACE1 ELISA kit |
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| 1-CSB-E09824h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human β-site APP-Cleaving Enzyme 1, BACE1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 ELISA Kit) Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Ra-48T | DL Develop | 48T | 609.6 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Ra-96T | DL Develop | 96T | 793.2 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Ra-48Tests | Reddot Biotech | 48 Tests | 613.2 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Ra-96Tests | Reddot Biotech | 96 Tests | 850.8 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Ra-48Tests | Reddot Biotech | 48 Tests | 640.8 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Ra-96Tests | Reddot Biotech | 96 Tests | 890.4 EUR |
ELISA Kit) Rat Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| QY-E10384 | Qayee Biotechnology | 96T | 433.2 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Ra-48T | Reddot Biotech | 48T | 465.47 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Ra-96T | Reddot Biotech | 96T | 664.97 EUR |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DL-bACE1-Ra | DL Develop | 96T | 432 EUR |
|
Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Ra | DL Develop | 96T | 454 EUR |
|
Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Ra-48T | Reddot Biotech | 48T | 443.3 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Ra-96T | Reddot Biotech | 96T | 633.3 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Ra-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | 5552.14 EUR |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Ra-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | 562.42 EUR |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Ra-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | 752.02 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Ra-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | 3024.07 EUR |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| 4-SEA718Ra | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from Serum, plasma, cerebrospinal fluid and other biological fluids. with no significant corss-reactivity with analogues from other species. |
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Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43822-48T | Biomatik Corporation | 48T | 370.02 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43822-5x96T | Biomatik Corporation | 5x96T | 2510.85 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43822-96T | Biomatik Corporation | 96T | 528.6 EUR |
Rat Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| YLA0293RA-48T | Shanghai YL Biotech | 48T | 465 EUR |
Rat Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| YLA0293RA-96T | Shanghai YL Biotech | 96T | 600 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| SL1515Ra | Sunlong | - | Ask for price |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKU02711-48T | Biomatik Corporation | 48T | 542.78 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKU02711-5x96T | Biomatik Corporation | 5x96T | 3683.15 EUR |
Rat Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKU02711-96T | Biomatik Corporation | 96T | 775.4 EUR |
 Human β-site APP-Cleaving Enzyme 1,BACE1 ELISA kit |
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| YLA1645HU-48T | Shanghai YL Biotech | 48T | 435 EUR |
Human β-site APP-Cleaving Enzyme 1,BACE1 ELISA kit |
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| YLA1645HU-96T | Shanghai YL Biotech | 96T | 562.5 EUR |
Human β-site APP-Cleaving Enzyme 1,BACE1 ELISA kit |
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| EKC36121-48T | Biomatik Corporation | 48T | 597.24 EUR |
Human β-site APP-Cleaving Enzyme 1,BACE1 ELISA kit |
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| EKC36121-5x96T | Biomatik Corporation | 5x96T | 4052.7 EUR |
Human β-site APP-Cleaving Enzyme 1,BACE1 ELISA kit |
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| EKC36121-96T | Biomatik Corporation | 96T | 853.2 EUR |
 ELISA Kit) Mouse Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx254802-96tests | Abbexa | 96 tests | 848.4 EUR |
 ELISA Kit) Human Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx252065-96tests | Abbexa | 96 tests | 904.8 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| 20-abx150780 | Abbexa |
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Mouse Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| abx574903-96tests | Abbexa | 96 tests | 801.6 EUR |
 ELISA Kit) Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Hu-48T | DL Develop | 48T | 574.8 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Hu-96T | DL Develop | 96T | 745.2 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, cerebrospinal fluid or other biological fluids. |
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 ELISA Kit) Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Mu-48T | DL Develop | 48T | 586.8 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, tissue homogenates, cerebrospinal fluid or other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Mu-96T | DL Develop | 96T | 762 EUR |
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Description: A sandwich quantitative ELISA assay kit for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, tissue homogenates, cerebrospinal fluid or other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (BACE1) ELISA Kit |
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| 20-abx153699 | Abbexa |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Hu-48Tests | Reddot Biotech | 48 Tests | 573.6 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Hu-96Tests | Reddot Biotech | 96 Tests | 794.4 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Mu-48Tests | Reddot Biotech | 48 Tests | 586.8 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Mu-96Tests | Reddot Biotech | 96 Tests | 812.4 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Hu-48Tests | Reddot Biotech | 48 Tests | 600 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Hu-96Tests | Reddot Biotech | 96 Tests | 830.4 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Mu-48Tests | Reddot Biotech | 48 Tests | 613.2 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Mu-96Tests | Reddot Biotech | 96 Tests | 850.8 EUR |
ELISA Kit) Mouse Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| QY-E20194 | Qayee Biotechnology | 96T | 433.2 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Hu-48T | Reddot Biotech | 48T | 432.39 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Hu-96T | Reddot Biotech | 96T | 617.72 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Mu-48T | Reddot Biotech | 48T | 443.42 EUR |
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Description: serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RDR-bACE1-Mu-96T | Reddot Biotech | 96T | 633.47 EUR |
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Description: serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DL-bACE1-Hu | DL Develop | 96T | 402 EUR |
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Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DL-bACE1-Mu | DL Develop | 96T | 412 EUR |
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Description: serum, plasma, tissue homogenates, cerebrospinal fluid or other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Hu | DL Develop | 96T | 422 EUR |
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Description: serum, plasma, cerebrospinal fluid or other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| DLR-bACE1-Mu | DL Develop | 96T | 432 EUR |
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Description: serum, plasma, tissue homogenates, cerebrospinal fluid or other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Hu-48T | Reddot Biotech | 48T | 411.8 EUR |
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Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Hu-96T | Reddot Biotech | 96T | 588.3 EUR |
|
Description: serum, plasma, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Mu-48T | Reddot Biotech | 48T | 422.3 EUR |
|
Description: serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| RD-bACE1-Mu-96T | Reddot Biotech | 96T | 603.3 EUR |
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Description: serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | 5128.02 EUR |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | 527.48 EUR |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | 702.12 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | 2799.54 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, cerebrospinal fluid and other biological fluids. |
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Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| 4-SEA718Hu | Cloud-Clone |
|
|
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from Serum, plasma, cerebrospinal fluid and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Mu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | 5269.39 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Mu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | 539.12 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| SEA718Mu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | 718.75 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
|||
| SEA718Mu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | 2874.38 EUR |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids. |
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Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| 4-SEA718Mu | Cloud-Clone |
|
|
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) in samples from serum, plasma, tissue homogenates, cerebrospinal fluid and other biological fluids with no significant corss-reactivity with analogues from other species. |
|||
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43820-48T | Biomatik Corporation | 48T | 341.04 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43820-5x96T | Biomatik Corporation | 5x96T | 2314.2 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43820-96T | Biomatik Corporation | 96T | 487.2 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43821-48T | Biomatik Corporation | 48T | 350.42 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43821-5x96T | Biomatik Corporation | 5x96T | 2377.85 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKN43821-96T | Biomatik Corporation | 96T | 500.6 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| YLA0024MO-48T | Shanghai YL Biotech | 48T | 465 EUR |
Mouse Beta-Site APP Cleaving Enzyme 1(bACE1)ELISA Kit |
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| YLA0024MO-96T | Shanghai YL Biotech | 96T | 600 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKU02709-48T | Biomatik Corporation | 48T | 500.5 EUR |
Human Beta-Site APP Cleaving Enzyme 1 (bACE1) ELISA Kit |
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| EKU02709-5x96T | Biomatik Corporation | 5x96T | 3396.25 EUR |
Treatment with nano extract restored metabolite ranges to regular and means that cytokine ranges have been regulated by nano extract in UC. Conclusion: ASBE nano extract mitigated in opposition to acetic acid-induced colitis in rats, and the underlying mechanism might be attributed to the modulatory results of ASBE on the inflammatory cascades. The applicability of metabolomics developed on this rat mannequin appears to be essential for evaluating the anti-inflammatory mechanisms of latest therapeutics for acute colitis.
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