Biochemical assay and spectroscopic analysis of oxidative/antioxidative parameters in the blood and serum of substance use disorders patients. A methodological comparison study
Substance abuse reminiscent of opioids, hashish, and alcohol causes activation on the immune system and the launch of reactive oxygen species (ROS) into the blood and serum. These substances trigger an impact on oxidant and antioxidant standing in sufferers with substance abuse. Mainly, wide-open to the ROS are lipids and proteins included blood, which suffers peroxidation. In this study, for the first-time differentiation of the results of hashish, alcohol and different artificial substances on blood and serum samples, have been carried out.
For this goal, the stage of the malondialdehyde (MDA) and glutathione (GSH) in serum and pink blood cells, was measured utilizing biochemical assay strategies and Fourier Transform InfraRed spectroscopy (FTIR). The outcomes confirmed, that peroxidation which is dignified as the manufacturing of MDA was elevated for substance use dysfunction (SUD) sufferers (18.01 ± 2.97) in comparison with the management group (10.75 ± 2.28) (p < 0.001) and for antioxidant capability, GSH stage have been considerably elevated for SUD sufferers (p < 0.001).
For the discrimination of protein and lipid area obtained from FTIR spectroscopy, we extracted options by principal part analyze (PCA) of protein (1800 cm-1 to 900 cm-1) and lipid (3200 cm-1 to 2800 cm-1) areas for blood and serum samples collected from sufferers with differing types of SUD and wholesome management (HC) contributors.
For the consideration of lipid oxidation, lipid saturation, lipid desaturation and protein aggregation the peak heights at 1740 cm-1 to 2960 cm-1, 2920 cm-1 to 2960 cm-1, 3012 cm-1 to 2960 cm-1, and 1630 cm-1 to 1650 cm-1 areas have been studied for SUD and HC. Moreover, extra seen modifications have been seen for proteins area, than for lipids. The most discover structural modifications have been noticed in amide II in serum spectra.
Then we categorized protein and lipid area’s PCA outcomes of blood and serum by Linear discriminant analysis (LDA) and Support vector machine (SVM). Confidence of the specificity, sensitivity and accuracy of blood and serum have been obtained as 100%, 100% and 100% individually. This is the first comparative study on the spectrochemical instrument and biochemical assay on SUD. Our outcomes offered 100% discrimination of dysfunction area in comparison with wholesome topics.
Development of a cell-free split-luciferase biochemical assay as a instrument for screening for inhibitors of difficult protein-protein interplay targets
Targeting the interplay of proteins with weak binding affinities or low solubility represents a selected problem for drug screening. The NanoLuc â ® Binary Technology (NanoBiT â ®) was initially developed to detect protein-protein interactions in stay mammalian cells. Here we report the profitable translation of the NanoBit mobile assay right into a biochemical, cell-free format utilizing mammalian cell lysates.
We present that the assay is appropriate for the detection of each robust and weak protein interactions reminiscent of these involving the binding of RAS oncoproteins to both RAF or phosphoinositide 3-kinase (PI3K) effectors respectively, and that it’s also efficient for the study of poorly soluble protein domains reminiscent of the RAS binding area of PI3K. Furthermore, the RAS interplay assay is delicate and responds to each robust and weak RAS inhibitors.
Our information present that the assay is strong, reproducible, cost-effective, and may be tailored for small and large-scale screening approaches. The NanoBit Biochemical Assay provides a horny instrument for drug screening in opposition to difficult protein-protein interplay targets, together with the interplay of RAS with PI3K.
Biochemical characterization of G protein coupling to calcitonin gene-related peptide and adrenomedullin receptors utilizing a local PAGE assay
Calcitonin gene-related peptide (CGRP), adrenomedullin (AM), and adrenomedullin 2/intermedin (AM2/IMD) have overlapping and distinctive features in the nervous and circulatory techniques together with vasodilation, cardioprotection, and ache transmission. Their actions are mediated by the class B calcitonin-like G protein-coupled receptor (CLR), which heterodimerizes with three receptor activity-modifying proteins (RAMP1-3) that decide its peptide ligand selectivity.
How the three agonists and RAMPs modulate CLR binding to transducer proteins stays poorly understood. Here, we biochemically characterised agonist-promoted G protein coupling to every CLR·RAMP complicated. We tailored a local PAGE technique to evaluate the formation and thermostabilities of detergent-solubilized fluorescent protein-tagged CLR·RAMP complexes expressed in mammalian cells.
Read More Here: Human Tumor Necrosis Factor Alpha (TNFA) ELISA Kit. Cat# abx050218. Supplier: abbexa
Addition of agonist and the purified Gs protein surrogate mini-Gs (mGs) yielded a mobility-shifted agonist·CLR·RAMP·mGs quaternary complicated gel band that was delicate to antagonists. Measuring the obvious affinities of the agonists for the mGs-coupled receptors and of mGs for the agonist-occupied receptors revealed that each ligand and RAMP management mGs coupling and outlined how agonist engagement of the CLR extracellular and transmembrane domains impacts transducer recruitment.
 ELISA Kit) Rat SNCb(Synuclein beta) ELISA Kit |
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| ELK8982-96T | ELK Biotech | 96T | Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SNCb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SNCb. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat SNCb, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat SNCb in the samples is then determined by comparing the OD of the samples to the standard curve. |
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 ELISA Kit) Human SNCb(Synuclein beta) ELISA Kit |
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| ELK8964-48T | ELK Biotech | 48T | Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SNCb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SNCb. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human SNCb, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human SNCb in the samples is then determined by comparing the OD of the samples to the standard curve. |
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Human SNCb(Synuclein beta) ELISA Kit |
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| ELK8964-96T | ELK Biotech | 96T | Ask for price |
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Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SNCb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SNCb. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human SNCb, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human SNCb in the samples is then determined by comparing the OD of the samples to the standard curve. |
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ELISA Kit) Human Synuclein Beta(SNCb)ELISA Kit |
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| QY-E01201 | Qayee Biotechnology | 96T | 433.2 EUR |
 alpha+beta Synuclein |
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| E8ET1609-66 | EnoGene | 100ul | 275 EUR |
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Description: Available in various conjugation types. |
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 beta Synuclein protein |
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| 30R-1010 | Fitzgerald | 100 ug | 219 EUR |
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Description: Purified recombinant Human beta Synuclein protein |
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beta Synuclein protein |
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| 30R-3034 | Fitzgerald | 200 ug | 424.8 EUR |
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Description: Purified recombinant beta Synuclein protein |
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 beta Synuclein Protein |
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| 20-abx260493 | Abbexa |
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 Beta Synuclein Protein |
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| SPR-405B | Stressmarq | 0.1 mg | 382 EUR |
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Description: Human Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-405C | Stressmarq | 2x0.1 mg | 611 EUR |
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Description: Human Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-405E | Stressmarq | 5x0.1 mg | 1240 EUR |
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Description: Human Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-406B | Stressmarq | 0.1 mg | 382 EUR |
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Description: Mouse Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-406C | Stressmarq | 2x0.1 mg | 611 EUR |
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Description: Mouse Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-406E | Stressmarq | 5x0.1 mg | 1240 EUR |
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Description: Mouse Recombinant Beta Synuclein Protein Monomers |
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Beta Synuclein Protein |
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| SPR-457B | Stressmarq | 0.1 mg | 382 EUR |
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Description: Human Recombinant Beta Synuclein Protein Pre-formed Fibrils (Type 1) |
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Beta Synuclein Protein |
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| SPR-457C | Stressmarq | 2x0.1 mg | 611 EUR |
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Description: Human Recombinant Beta Synuclein Protein Pre-formed Fibrils (Type 1) |
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Beta Synuclein Protein |
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| SPR-457E | Stressmarq | 5x0.1 mg | 1240 EUR |
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Description: Human Recombinant Beta Synuclein Protein Pre-formed Fibrils (Type 1) |
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 beta Synuclein Antibody |
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| GWB-409C5B | GenWay Biotech | 0.5 ml | Ask for price |
 Beta synuclein antibody |
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| 70R-50407 | Fitzgerald | 100 ul | 242 EUR |
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Description: Purified Polyclonal Beta synuclein antibody |
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 Synuclein beta Antibody |
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| AF5324 | Affbiotech | 200ul | 420 EUR |
Synuclein beta Antibody |
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| AF5324-100ul | Affinity Biosciences | 100ul | 280 EUR |
Synuclein beta Antibody |
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| AF5324-200ul | Affinity Biosciences | 200ul | 350 EUR |
 Synuclein beta antibody |
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| 70R-30765 | Fitzgerald | 100 ug | 294 EUR |
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Description: Rabbit polyclonal Synuclein beta antibody |
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 Protein) Beta synuclein (SNCB) Protein |
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| abx260493-01mg | Abbexa | 0.1 mg | 2487.5 EUR |
Beta synuclein (SNCB) Protein |
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| abx260493-10g | Abbexa | 10 µg | 325 EUR |
Beta synuclein (SNCB) Protein |
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| abx260493-2g | Abbexa | 2 µg | 225 EUR |
 Antibody) Beta synuclein (SNCB) Antibody |
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| 20-abx329387 | Abbexa |
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Beta synuclein (SNCB) Antibody |
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| abx332342-100ul | Abbexa | 100 ul | 510 EUR |
 Antibody) beta Synuclein (SNCB) Antibody |
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| 20-abx008696 | Abbexa |
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Beta synuclein (SNCB) Antibody |
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| abx329387-100g | Abbexa | 100 µg | Ask for price |
Beta synuclein (SNCB) Antibody |
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| abx329387-20g | Abbexa | 20 µg | 187.5 EUR |
Beta synuclein (SNCB) Antibody |
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| abx329387-50g | Abbexa | 50 µg | 250 EUR |
 alpha beta Synuclein antibody |
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| 10R-1043 | Fitzgerald | 100 ul | 320 EUR |
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Description: Mouse monoclonal alpha, beta Synuclein antibody |
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 alpha+beta Synuclein Antibody |
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| 48903 | SAB | 100ul | 499 EUR |
alpha+beta Synuclein Antibody |
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| 48903-100ul | SAB | 100ul | 399.6 EUR |
alpha+beta Synuclein Antibody |
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| 48903-50ul | SAB | 50ul | 286.8 EUR |
 beta synuclein Blocking Peptide |
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| 20-abx063282 | Abbexa |
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 Antibody) Synuclein Beta (SNCb) Antibody |
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| abx218848-100ug | Abbexa | 100 ug | 526.8 EUR |
Synuclein Beta (SNCb) Antibody |
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| 20-abx116915 | Abbexa |
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Synuclein Beta (SNCb) Antibody |
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| abx116915-100g | Abbexa | 100 µg | 612.5 EUR |
Synuclein Beta (SNCb) Antibody |
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| abx218848-100tests | Abbexa | 100 tests | Ask for price |
Synuclein Beta (SNCb) Antibody |
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| abx218848-200tests | Abbexa | 200 tests | Ask for price |
Synuclein Beta (SNCb) Antibody |
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| abx218848-20tests | Abbexa | 20 tests | 350 EUR |
 alpha + beta Synuclein Rabbit pAb |
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| E2380962 | EnoGene | 100ul | 225 EUR |
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Description: Available in various conjugation types. |
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 alpha + beta Synuclein Rabbit mAb |
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| A4899 | Abclonal | 200μL | 83.2 EUR |
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Description: A synthetic peptide corresponding to a sequence within amino acids 100-207 of human RAB8A (P61006). |
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alpha + beta Synuclein Rabbit mAb |
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| 56061 | SAB | 100ul | 339 EUR |
 alpha/beta Synuclein Rabbit mAb |
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| E2R380962 | EnoGene | 100ul | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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 Synuclein beta Blocking Peptide |
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| AF5324-BP | Affbiotech | 1mg | 234 EUR |
 Antibody) Anti-β-Synuclein (Ab-125) Antibody |
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| Y021248 | ABM | 100 µg | 285 EUR |
 alpha+beta Synuclein Conjugated Antibody |
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| C48903 | SAB | 100ul | 476.4 EUR |
) beta Synuclein Antibody (ready-to-use) |
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| GWB-96DD67 | GenWay Biotech | 7 ml | Ask for price |
 Rat Alpha Synuclein ELISA kit |
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| E02S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Alpha Synuclein ELISA kit |
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| E02S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Alpha Synuclein ELISA kit |
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| E02S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Dog Alpha Synuclein ELISA kit |
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| E08S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Alpha Synuclein ELISA kit |
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| E08S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Alpha Synuclein ELISA kit |
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| E08S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Pig Alpha Synuclein ELISA kit |
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| E07S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Alpha Synuclein ELISA kit |
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| E07S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Alpha Synuclein ELISA kit |
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| E07S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Alpha Synuclein ELISA kit |
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| E01A16445 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Goat Alpha Synuclein ELISA kit |
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| E01A51348 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Goat Alpha Synuclein ELISA kit |
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| E06S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Goat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Alpha Synuclein ELISA kit |
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| E06S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Goat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat Alpha Synuclein ELISA kit |
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| E06S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Goat Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rabbit polyclonal Synuclein beta antibody |
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| TA312076 | Origene Technologies GmbH | 100 µl | Ask for price |
 Antibody) Anti-β-Synuclein (Phospho-Tyr133) Antibody |
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| Y011285 | ABM | 100 µg | 285 EUR |
 Antibody) Anti-β-Synuclein (Phospho-Tyr136) Antibody |
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| Y011286 | ABM | 100 µg | 285 EUR |
 Sheep Alpha Synuclein ELISA kit |
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| E01A103642 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Mouse Alpha Synuclein ELISA kit |
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| E01A25192 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Mouse Alpha Synuclein ELISA kit |
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| E03S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Mouse Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Alpha Synuclein ELISA kit |
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| E03S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Mouse Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse Alpha Synuclein ELISA kit |
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| E03S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Mouse Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Human Alpha Synuclein ELISA kit |
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| E01A7700 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Human Alpha Synuclein ELISA kit |
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| E01S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Human Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Alpha Synuclein ELISA kit |
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| E01S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Human Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human Alpha Synuclein ELISA kit |
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| E01S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Human Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Mouse Gamma- Synuclein ELISA Kit |
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| ELA-E1271m | Lifescience Market | 96 Tests | 1038 EUR |
 Synuclein Cell ELISA Kit |
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| abx595580-96tests | Abbexa | 96 tests | 764.4 EUR |
Synuclein Cell ELISA Kit |
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| abx595580-100g | Abbexa | 100 µg | Ask for price |
Synuclein Cell ELISA Kit |
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| abx595580-10g | Abbexa | 10 µg | 493.75 EUR |
Synuclein Cell ELISA Kit |
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| abx595580-50g | Abbexa | 50 µg | Ask for price |
 Rabbit Alpha Synuclein ELISA kit |
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| E01A33914 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Canine Alpha Synuclein ELISA kit |
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| E01A68776 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Bovine Alpha Synuclein ELISA kit |
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| E01A86215 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Monkey Alpha Synuclein ELISA kit |
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| E01A77495 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Monkey Alpha Synuclein ELISA kit |
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| E09S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Monkey Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Alpha Synuclein ELISA kit |
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| E09S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Monkey Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey Alpha Synuclein ELISA kit |
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| E09S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Monkey Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Alpha Synuclein ELISA kit |
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| E04S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Alpha Synuclein ELISA kit |
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| E04S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit Alpha Synuclein ELISA kit |
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| E04S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rabbit Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Porcine Alpha Synuclein ELISA kit |
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| E01A60066 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Chicken Alpha Synuclein ELISA kit |
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| E01A94927 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 anti-beta Synuclein |
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| YF-PA14711 | Abfrontier | 50 ug | 435.6 EUR |
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Description: Mouse polyclonal to beta Synuclein |
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 Anti-alpha+beta Synuclein Antibody [ST05-21] |
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| ET1609-66 | HUABIO | 100ul | 231 EUR |
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Description: The synucleins, including α-synuclein (also designated NACP for nonamyloid component precursor), β-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and γ-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-Synuclein, identified as a component of Alzheimer’s disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of α-synuclein and β-synuclein may be important during hematopoetic cell differentiation. A mutant form of α-synuclein is found in patients with early onset Parkinson’s disease. γ-Synuclein is associated with axonal pathology in Parkinson’s disease. |
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 - Mouse synuclein, beta (Sncb)) Sncb (GFP-tagged) - Mouse synuclein, beta (Sncb) |
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| MG200783 | Origene Technologies GmbH | 10 µg | Ask for price |
 alpha+beta Synuclein recombinant monoclonal antibody |
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| A5623 | Bimake | 100ul X 3 | 714 EUR |
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Description: A recombinant monoclonal antibody from rabbit against human alpha+beta Synuclein for WB ,ELISA |
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 Guinea Pig Alpha Synuclein ELISA kit |
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| E01A42631 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Guinea pig Alpha Synuclein ELISA kit |
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| E05S0033-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Guinea pig Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Guinea pig Alpha Synuclein ELISA kit |
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| E05S0033-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Guinea pig Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Guinea pig Alpha Synuclein ELISA kit |
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| E05S0033-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Guinea pig Alpha Synuclein in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Rabbit anti Synuclein beta Polyclonal Antibody |
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| TA354230 | Origene Technologies GmbH | 100 µg | Ask for price |
 Human ?-Synuclein,?-SYN ELISA Kit |
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| 201-12-1314 | SunredBio | 96 tests | 528 EUR |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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 Rat Synuclein, Alpha ELISA kit |
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| E02S0131-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Synuclein, Alpha ELISA kit |
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| E02S0131-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Synuclein, Alpha ELISA kit |
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| E02S0131-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Rat Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Dog Synuclein, Alpha ELISA kit |
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| E08S0131-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Synuclein, Alpha ELISA kit |
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| E08S0131-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog Synuclein, Alpha ELISA kit |
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| E08S0131-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Canine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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 Pig Synuclein, Alpha ELISA kit |
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| E07S0131-192T | BlueGene | 192 tests | 1524 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Synuclein, Alpha ELISA kit |
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| E07S0131-48 | BlueGene | 1 plate of 48 wells | 624 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig Synuclein, Alpha ELISA kit |
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| E07S0131-96 | BlueGene | 1 plate of 96 wells | 822 EUR |
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Description: A sandwich ELISA for quantitative measurement of Porcine Synuclein, Alpha in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat Synuclein, Alpha ELISA kit |
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| E01A16493 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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 Goat Synuclein, Alpha ELISA kit |
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| E01A51396 | BlueGene | 96T | 700 EUR |
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Description: ELISA |
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Using mini-Gsq and -Gsi chimeras, we noticed a coupling rank order of mGs > mGsq > mGsi for every receptor. Last, we demonstrated the physiological relevance of the native gel assays by exhibiting that they’ll predict the cAMP-signaling potencies of AM and AM2/IMD chimeras. These outcomes spotlight the energy of the native PAGE assay for membrane protein biochemistry and present a biochemical basis for understanding the molecular foundation of shared and distinct signaling properties of CGRP, AM, and AM2/IMD.
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