Description: A polyclonal antibody for detection of RPTOR from Human. This RPTOR antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human RPTOR protein at amino acid sequence of 730-810

Description: A polyclonal antibody against RPTOR. Recognizes RPTOR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Description: Unconjugated Rabbit polyclonal to RPTOR

Description: A polyclonal antibody against RPTOR. Recognizes RPTOR from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against RPTOR. Recognizes RPTOR from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

Description: A polyclonal antibody against RPTOR. Recognizes RPTOR from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Description: A Monoclonal antibody against Human RPTOR. The antibodies are raised in Mouse and are from clone 6G9C4. This antibody is applicable in WB, E

Description: A Monoclonal antibody against Human RPTOR. The antibodies are raised in Mouse and are from clone 1411CT316.2.151.34. This antibody is applicable in WB and IHC-P, E

Description: Description of target: Involved in the control of the mammalian target of rapamycin complex 1 (mTORC1) activity which regulates cell growth and survival, and autophagy in response to nutrient and hormonal signals; functions as a scaffold for recruiting mTORC1 substrates. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Involved in ciliogenesis.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 40.1 pg/mL

Description: Description of target: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.1 ng/mL