Description: A sandwich quantitative ELISA assay kit for detection of Human 2',5'-Oligoadenylate Synthetase Like Protein (OASL) in samples from serum, plasma, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human 2',5'-Oligoadenylate Synthetase Like Protein (OASL) in samples from serum, plasma, cell lysates or other biological fluids.

Description: A polyclonal antibody against OASL. Recognizes OASL from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1:500-2000, ELISA:1:10000-20000

Description: A polyclonal antibody against OASL. Recognizes OASL from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100

Description: A polyclonal antibody against OASL. Recognizes OASL from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100

Description: Rabbit polyclonal OASL antibody raised against the middle region of OASL

Description: Rabbit polyclonal OASL antibody raised against the N terminal of OASL

Description: OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains (1). It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor (4).

Description: OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains (1). It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor (4).

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human OASL (N-Terminus). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human OASL (C-term). This antibody is tested and proven to work in the following applications:

Description: Rabbit polyclonal to OASL.

Description: (NT) OASL Peptide

Description: A cloning plasmid for the OASL gene.

Description: A synthetic peptide for use as a blocking control in assays to test for specificity of OASL antibody, catalog no. 70R-5888

Description: A synthetic peptide for use as a blocking control in assays to test for specificity of OASL antibody, catalog no. 70R-5891

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL)

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with PE.

Description: Description of target: Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.3 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.2"Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase."_x005F_x005F_x000D_Rebouillat D., Marie I., Hovanessian A.G._x005F_x005F_x000D_Eur. J. Biochem. 257:319-330(1998) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS P56 AND P30), FUNCTION, SUBCELLULAR LOCATION.Ref.10"The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain."_x005F_x005F_x000D_Marques J., Anwar J., Eskildsen-Larsen S., Rebouillat D., Paludan S.R., Sen G., Williams B.R., Hartmann R._x005F_x005F_x000D_J. Gen. Virol. 89:2767-2772(2008) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.13"2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro."_x005F_x005F_x000D_Ishibashi M., Wakita T., Esumi M._x005F_x005F_x000D_Biochem. Biophys. Res. Commun. 392:397-402(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INDUCTION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 6.8 pg/mL

Description: A Rabbit polyclonal antibody against Human 2', 5'-Oligoadenylate Synthetase Like Protein (OASL). This antibody is labeled with APC-Cy7.