matched Antibody

matched Antibody

PDL1 ELISA Matched Antibody Pair (Risk Free)

RFP-0306 ProSci 1 Set 745.8 EUR
Description: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

PDL1 ELISA Matched Antibody Pair (Risk Free)

RFP-0307 ProSci 1 Set 752.1 EUR
Description: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

TIGIT ELISA Matched Antibody Pair (Risk Free)

RFP-0501 ProSci 1 Set 752.1 EUR
Description: TIGIT Antibody: The T cell immunoreceptor with Ig and ITIM domains (TIGIT) is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. It is expressed on several classes of T cells including follicular B helper T cells (TFH). TIGIT has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses (1). Similar to other immune checkpoint proteins such as PD-1, TIGIT is upregulated on exhausted T cells in chronic viral infections and cancer. Blockade of both TIGIT and PD-1 pathways leads to tumor rejection in mice suggesting that it may be of therapeutic use against cancer (2).

Fibrinogen Matched Pair antibody Set

55R-FIBRINO-KT Fitzgerald set 999.6 EUR
Description: Fibrinogen Matched Pair antibody Set for detection of Human Fibrinogen in the research laboratory

TIM-3 ELISA Matched Antibody Pair (Risk Free)

RFP-1001 ProSci 1 Set 752.1 EUR
Description: The immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-γ producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice; blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

Human IL6 matched pair antibody kit

55R-M9316clb Fitzgerald 1 kit 2295.6 EUR
Description: PeliPair matched pair Human IL6 antibodies and antigen for ELISA assays

Human IL8 matched pair antibody kit

55R-M9318clb Fitzgerald 1 kit 2295.6 EUR
Description: PeliPair matched pair Human IL8 antibodies and antigen for ELISA assays

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Colon

C8235090-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Liver

C8235149-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Lung

C8235152-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Breast

C8235086-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Kidney

C8235142-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Rectum

C8235206-PM Biochain 10 reactions x2 1102 EUR

Matched Pair - cDNA - Human Primary and Matched Metastatic Tumor Tissue: Stomach

C8235248-PM Biochain 10 reactions x2 1102 EUR

Sample Cell 10ml Matched

2495402 Scientific Laboratory Supplies PK2 409.2 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Lung

T6235152-PM Biochain 5 slides x2 736 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Breast

T6235086-PM Biochain 5 slides x2 736 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Colon

T6235090-PM Biochain 5 slides x2 736 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney

T6235142-PM Biochain 5 slides x2 736 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Liver

T6235149-PM Biochain 5 slides x2 736 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Rectum

T6235206-PM Biochain 5 slides x2 1088 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Lung

T8235152-PM Biochain 5 slides x2 626 EUR

Matched Pair - Frozen Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Stomach

T6235248-PM Biochain 5 slides x2 736 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Breast

T8235086-PM Biochain 5 slides x2 626 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Colon

T8235090-PM Biochain 5 slides x2 626 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Kidney

T8235142-PM Biochain 5 slides x2 626 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Liver

T8235149-PM Biochain 5 slides x2 626 EUR

Matched Pair - Paraffin Tissue Section - Human Primary and Matched Metastatic Tumor (PM): Rectum

T8235206-PM Biochain 5 slides x2 626 EUR

Matched Pair - Paraffin Tissue Sections - Human Primary and Matched Metastatic Tumor (PM): Stomach

T8235248-PM Biochain 5 slides x2 626 EUR

Matched Pair Tissue Slides - Lung Tissue

10-100-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Skin Tissue

12-700-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Liver Tissue

10-200-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Kidney Tissue

10-400-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Spleen Tissue

10-900-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Breast Tissue

10-000-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Cervix Tissue

11-300-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Stomach Tissue

10-800-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Bladder Tissue

12-600-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Matched Pair Tissue Slides - Colorectal Tissue

10-700-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Colon cancer with matched colon tissue array

CO1801a TissueArray each 474 EUR
Description: Colon cancer with matched colon tissue array, including pathology grade,with MMR (MLH1/PMS2/MSH2/MSH6) IHC results, TNM and clinical stage, containing 90 cases of adenocarcinoma, and 90 cancer adjacent or adjacent normal colon tissue, 90 cases/180 cores, replacing CO1801

Colon cancer with matched colon tissue array

CO602a TissueArray each 222 EUR
Description: Colon cancer with matched colon tissue array, including pathology grade, TNM and clinical stage, 30 cases/60 cores, replacing CO602

Colon cancer with matched colon tissue array

CO703 TissueArray each 198 EUR
Description: Colon cancer with matched colon tissue array, including pathology grade, TNM and clinical stage, 35 cases/70 cores,replaced by CO703a

Liver cancer with matched liver tissue array

LV241b TissueArray each 66 EUR
Description: Liver cancer with matched liver tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing LV241a

SARS-CoV-2 (COVID-19) Spike Matched Pair

MPS-0001 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).

SARS-CoV-2 (COVID-19) Spike Matched Pair

MPS-0002 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).

SARS-CoV-2 (COVID-19) Spike Matched Pair

MPS-0003 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).

SARS-CoV-2 (COVID-19) Spike Matched Pair

MPS-0004 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).

SARS-CoV-2 (COVID-19) Spike Matched Pair

MPS-0005 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).

Breast cancer with matched breast tissue array

BR251e TissueArray each 60 EUR
Description: Breast cancer with matched breast tissue array, including pathology grade, IHC info (ER,PR,Her-2,Ki67),TNM\Stage, 6 cases/24 cores (core size 1.5mm), replacing BR251d

Kidney cancer with matched kidney tissue array

KD801a TissueArray each 258 EUR
Description: Kidney cancer with matched kidney tissue array, including pathology grade, TNM and clinical stagr, 40 cases/80 cores, replacing KD801

Matched Pair Tissue Slides - Small Intestine Tissue

11-800-MPPT ProSci 1 pack 241.8 EUR
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Breast carcinoma with matched breast tissue array

BR251f TissueArray each 60 EUR
Description: Breast carcinoma with matched breast tissue array, including pathology grade, IHC info(ER\PR\Her-2\Ki67), TNM\Sstage, 6 cases/24 cores (core size 1.5mm), replacing BR251e

Kidney carcinoma with matched kidney tissue array

KD244a TissueArray each 48 EUR
Description: Kidney carcinoma with matched kidney tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing KD244

Lung cancer and matched adjacent lung tissue array

LC486 TissueArray each 168 EUR
Description: Lung cancer and matched adjacent lung tissue array, including TNM and pathology grade, 16 cases/48 cores

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0001 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0002 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0003 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0004 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0005 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0006 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

SARS-CoV-2 (COVID-19) Nucleocapsid Matched Pair

MPN-0007 ProSci 1 Set 1029.3 EUR
Description: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2). Nucleocapsid (N) protein is the most abundant protein of coronavirus. It is also one of the major structural proteins and is involved in the transcription and replication of viral RNA, packaging of the encapsidated genome into virions (3), and interference with cell cycle processes of host cells (4). Moreover, in many coronaviruses, including SARS-CoV, the N protein has high immunogenic activity and is abundantly expressed during infection (5). It can be detected in various patient samples including nasopharyngeal aspirate, urine, and fecal. Both S and N proteins may be potential antigens for serodiagnosis of COVID-19, just as many diagnostic methods have been developed for diagnosing SARS based on S and/or N proteins (6).

Brain tumor with matched adjacent normal tissue array

GL808 TissueArray each 306 EUR
Description: Brain tumor with matched adjacent normal tissue array, including pathology grade, 80 cases/80 cores, replacing GL801

Pancreatitis and matched pancreatic cancer tissue array

PA485 TissueArray each 222 EUR
Description: Pancreatitis and matched pancreatic cancer tissue array, including TNM, clinical stage and pathology grade, 43 cases/48 cores

Colon cancer with matched adjacent normal colon tissue

CO321a TissueArray each 168 EUR
Description: Colon cancer with matched adjacent normal colon tissue, including pathology grade, TNM and clinical stage, 16 cases/32 cores, replacing CO321

Colonic adenocarcinoma and matched adjacent tissue array

CO481 TissueArray each 198 EUR
Description: Colonic adenocarcinoma and matched adjacent tissue array, with TNM data, 12 cases/48 cores

Stomach carcinoma with matched stomach tissue microarray

ST2084b TissueArray each 546 EUR
Description: Stomach carcinoma with matched stomach tissue microarray, containing 94 cases of adenocarcinoma, 1 each of signet ring cell carcinoma and squamous cell carcinoma, duplicated cores per case

Stomach adenocarcinoma with matched stomach tissue array

ST781 TissueArray each 270 EUR
Description: Stomach adenocarcinoma with matched stomach tissue array, including pathology grade, TNM and clinical stage, 26 cases/78 cores

Multiple kidney cancer with matched kidney tissue array

KD461 TissueArray each 258 EUR
Description: Multiple kidney cancer with matched kidney tissue array, including pathology grade, TNM and clinical stage, 23 cases/46 cores

Rectum cancer with matched adjacent normal tissue array

RE801 TissueArray each 270 EUR
Description: Rectum cancer with matched adjacent normal tissue array, including pathology grade, TNM and clinical stage, 40 cases/80 cores

Stomach cancer with matched cancer adjacent tissue array

ST1504 TissueArray each 258 EUR
Description: Stomach cancer with matched cancer adjacent tissue array, including pathology grade, TNM and clinical stage, 50 cases/150 cores

Breast cancer and matched metastatic carcinoma tissue array

BR10010f TissueArray each 354 EUR
Description: Breast cancer and matched metastatic carcinoma tissue array, including TNM and pathology grade,IHC (ER,PR,Her-2,Ki67) markers results, 50 cases/100 cores, replacing BR10010e

Breast cancer and matched metastatic carcinoma tissue array

BR20837a TissueArray each 546 EUR
Description: Breast cancer and matched metastatic carcinoma tissue array, including TNM, clinical stage and pathology grade, 104 cases/ 208 cores, replacing BR20837