Description: A polyclonal antibody for detection of FAS-L from Human, Mouse. This FAS-L antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FAS-L at AA range: 70-150

Description: A Rabbit Polyclonal antibody against FAS-L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS-L from Human/Mouse. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS-L from Human. This antibody is tested and validated for IHC, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS-L from Human. This antibody is tested and validated for IHC, WB, ELISA

Description: A polyclonal antibody for detection of FAS-L from Human. This FAS-L antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FAS-L protein at amino acid sequence of 121-170

Description: A polyclonal antibody for detection of FAS-L from Human. This FAS-L antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FAS-L protein at amino acid sequence of 121-170

Description: A polyclonal antibody for detection of FAS-L from Human. This FAS-L antibody is for IHC-P, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human FAS-L protein at amino acid sequence of 121-170

Description: FAS-L is a protein encoded by the FASLG gene which is approximately 31,4 kDa. FAS-L is localised to the cell membrane and is involved in PEDF induced signalling, dimerization of procaspase-8, apoptosis modulation and signalling and the TNFR1 pathway. FAS-L is a member of the tumor necrosis factor superfamily. It is a cytokine that binds to TNFRSF6/FAS which is a receptor that transduces the apoptotic signal into cells. It may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. FAS-L is expressed in the blood, spleen, lymph nodes, intestine and kidney. Mutations in the FASLG gene result in autoimmune lymphoproliferative syndrome 1B. STJ93042 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of FAS-L protein.

Description: Rabbit polyclonal to FAS-L.

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the non-phosphorylation site of Y291

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the non-phosphorylation site of Y291

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the non-phosphorylation site of Y291

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FAS

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FAS

Description: A polyclonal antibody for detection of FAS from Human. This FAS antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human FAS

Description: A Rabbit Polyclonal antibody against FAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS from Human. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FAS . This antibody is tested and proven to work in the following applications:

Description: A sandwich quantitative ELISA assay kit for detection of Human Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Human Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Mouse Factor Related Apoptosis (FAS) in samples from serum, plasma or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Mouse Factor Related Apoptosis (FAS) in samples from serum, plasma or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Porcine Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Porcine Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Rat Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Monkey Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: A sandwich quantitative ELISA assay kit for detection of Monkey Factor Related Apoptosis (FAS) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Description: Description of target: FAS Ligand (FASL) is a 40 kDa type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M (r) of 31,759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas.;Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Fas/Apo1 . This antibody is tested and proven to work in the following applications:

Description: Rabbit Monoclonal Fas/Cd95 Antibody. Validated in IF, WB and tested in Human.

Description: A Rabbit Polyclonal antibody against FAS (phospho Tyr291) from Human. This antibody is tested and validated for IF, WB, ELISA

Description: A Rabbit Polyclonal antibody against FAS (phospho Tyr291) from Human. This antibody is tested and validated for IF, WB, ELISA

Description: A polyclonal antibody for detection of FAS phospho Tyr291) from Human. This FAS phospho Tyr291) antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the phosphorylation site of Y291

Description: A polyclonal antibody for detection of FAS phospho Tyr291) from Human. This FAS phospho Tyr291) antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the phosphorylation site of Y291

Description: A polyclonal antibody for detection of FAS phospho Tyr291) from Human. This FAS phospho Tyr291) antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human FAS around the phosphorylation site of Y291

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Phospho-FAS(Y291) . This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FASLG / Fas Ligand . This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CD95 / FAS (Internal). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Description: A polyclonal antibody against fas. Recognizes fas from Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:5000

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:50-1:500

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/20000

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

Description: Rabbit polyclonal FAS antibody

Description: Affinity purified rabbit polyclonal FAS antibody

Description: Rabbit polyclonal FAS antibody

Description: Rabbit polyclonal FAS antibody

Description: Affinity purified Rabbit polyclonal FAS antibody

Description: Mouse monoclonal Fas antibody

Description: Mouse monoclonal Fas antibody

Description: Rabbit polyclonal Fas antibody

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Description: A polyclonal antibody against FAS. Recognizes FAS from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

Description: A sandwich ELISA for quantitative measurement of Rabbit FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Rabbit FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Rabbit FAS Ligand in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: Recombinant clonal CHO cell line stably expressing full length human claudin 18.2 (claudin 18 isoform 2, CLDN 18.2, gene accession number NM_001002026.3). The stable clonal cell line was selected for different levels of Claudin 18.2 expression (High, Medium, and Low) compared to the parental CHO-K1 cell line.

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD95 / FAS (aa281-330). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CD95 / FAS (N-Terminus). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Goat that recognizes and binds to Human FAS / CD95 (internal region). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Neurofilament L (NF-L) . This antibody is tested and proven to work in the following applications:

Description: Rabbit polyclonal FAS antibody (Tyr291)

Description: Rabbit polyclonal FAS ligand antibody

Description: Mouse monoclonal Fas Ligand antibody

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Description: Rabbit polyclonal to FAS.

Description: FAS is a protein encoded by the FAS gene which is approximately 37,7 kDa. FAS isoform 1 is localised to the cell membrane with other isoforms being secreted. It is involved in dimerization of procaspase-8, allograft rejection, apoptosis modulation and signalling, PEDF induced signalling and the TNFR1 pathway. This protein falls under the TNF-receptor superfamily. This receptor contains a death domain and plays a central role in the physiological regulation of programmed cell death, it has also been implicated in the pathogenesis of various malignancies and diseases of the immune system. FAS isoform 1 and 6 is expressed in resting peripheral blood mononuclear cells. Mutations in the FAS gene may result in autoimmune lymphoproliferative syndrome. STJ93041 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of FAS protein.

Description: Mouse monoclonal to FAS.

Description: Mouse monoclonal to FAS.

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: FAS (also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. FAS antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor (TNF) receptors and the low-affinity nerve growth factor receptor (NGFR) and it is mapped to 10q24.1. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signaling pathway has been shown to participate in immune escape and tumorigenesis.

Description: mAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: mAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: mAb B-R18 specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45kDa, containing 8kDa of N-glycosidic-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

Description: A competitive ELISA for quantitative measurement of Rabbit Fas/APO 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rabbit Fas/APO 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A competitive ELISA for quantitative measurement of Rabbit Fas/APO 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: Recombinant clonal CHO-K1 stable cell line constitutively expressing full-length human NCAM1 protein (Neural cell adhesion molecule 1, also known as CD56, single-pass type I membrane protein, isoform 1- Seq ID: NM_000615). _x000D_The NCAM1 (CD56) CHO cell line is provided as three different stable, clonal cell lines. Each cell line was selected for different levels of NCAM1 expression: low (L), medium (M) or high (H). Variable expression levels are advantageous for validating antibodies or compounds in binding assays.  A drug discovery program may find value in owning all three clones with differential expression of NCAM1. The surface expression of NCAM1 in each cell line was validated in parallel by flow cytometry. 

Description: Recombinant hEGFRvIII-CHO K1 cell line stably expressing full-length human EGFRvIII receptor (accession number NP_001333870). Surface expression of hEGFRvIII was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of hEGFRvIII expression (High and Low) to mimic different stages of cancer target cells with various EGFRvIII expression levels.

Description: This cell line is a clonal derivative from the Cas9-Expressing MDA-MB-231 Cell Pool (BPS Bioscience, #78069). It was generated by limited limiting dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a low- or high-expressing cell line. The expressed Cas9 protein includes a C-terminal FLAG tag.

Description: Recombinant FAP-CHO K1 cell line stably expressing a full length human FAP-alpha protein (Genbank accession No: NM004460.2). Surface expression of FAP was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of FAP expression (High, Medium, or Low) to mimic different stages of cancer target cells with various FAP expression levels.

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FASLG / Fas Ligand (N-Terminus). This antibody is tested and proven to work in the following applications:

Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FASLG / Fas Ligand (N-Terminus). This antibody is tested and proven to work in the following applications:

Description: A Rabbit polyclonal antibody against Bovine Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Human Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Mouse Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Pig Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Description: A Rabbit polyclonal antibody against Rat Factor Related Apoptosis (FAS)

Description: A polyclonal antibody for detection of Crk-L from Human, Mouse, Rat, Monkey. This Crk-L antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Crk-L around the non-phosphorylation site of Y207

Description: A polyclonal antibody for detection of Crk-L from Human, Mouse, Rat, Monkey. This Crk-L antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Crk-L around the non-phosphorylation site of Y207