ALEXA FLUOR 555 Antibody
ALEXA FLUOR 555 Antibody
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STJ170000 | St John's Laboratory | 100 µg | EUR 393 |
Description: CD40 (48 to 50 kDa) is a transmembrane glycoprotein mainly expressed on the surface of B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily, which includes the low affinity nerve growth factor (NGF) receptor and CD95/Fas. CD40 is the receptor for CD40 ligand. CD40L (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40, predominantly on activated CD4+ T cells. Following interaction with CD40 ligand, CD40 mediates a number of major immunoregulatory functions, central to the control of thymus dependent humoral immunity and may be critical in the development of cell mediated immune responses. Other biological actions include B cell homotypic adhesion, proliferation, immunoglobulin isotype switch, and secretion. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin |
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STJ170004 | St John's Laboratory | 100 µg | EUR 393 |
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface. |
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STJ170005 | St John's Laboratory | 100 µg | EUR 393 |
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface. |
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STJ170006 | St John's Laboratory | 100 µg | EUR 393 |
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface. |
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STJ170009 | St John's Laboratory | 100 µg | EUR 393 |
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment |
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STJ170010 | St John's Laboratory | 100 µg | EUR 393 |
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment |
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STJ170011 | St John's Laboratory | 100 µg | EUR 393 |
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment |
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STJ170014 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
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STJ170015 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
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STJ170016 | St John's Laboratory | 100 µg | EUR 393 |
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307) |
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STJ170020 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
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STJ170021 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
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STJ170022 | St John's Laboratory | 100 µg | EUR 393 |
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54) |
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abx098902-100tests | Abbexa | 100 tests | EUR 1233 |
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abx098904-60tests | Abbexa | 60 tests | EUR 1358 |
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A4-829-C100 | ExBio | 0.1 mg | EUR 310 |
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A4-646-T100 | ExBio | 100 tests | EUR 269 |
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43R-1649 | Fitzgerald | 500 ug | EUR 570 |
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488) |
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1795 | AAT Bioquest | 10 mg | EUR 393 |
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20102-101-A555 | Alpha Diagnostics | 50 Tests | EUR 263 |
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A4-310-T100 | ExBio | 100 tests | EUR 269 |
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A4-354-C100 | ExBio | 0.1 mg | EUR 269 |
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A7-455-T100 | ExBio | 100 tests | EUR 269 |
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A7-727-T100 | ExBio | 100 tests | EUR 269 |
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A7-789-T100 | ExBio | 100 tests | EUR 269 |
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43R-ID005AF | Fitzgerald | 500 ug | EUR 338 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594) |
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43R-ID022AF | Fitzgerald | 500 ug | EUR 364 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
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43R-ID028AF | Fitzgerald | 500 ug | EUR 430 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647) |
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43R-ID047AF | Fitzgerald | 500 ug | EUR 462 |
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594) |
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43R-ID056AF | Fitzgerald | 500 ug | EUR 343 |
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594) |
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43R-ID060AF | Fitzgerald | 300 ug | EUR 425 |
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647) |
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43R-IR016AF | Fitzgerald | 1 mg | EUR 281 |
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594) |
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16890 | AAT Bioquest | 1 mg | EUR 176 |
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16891 | AAT Bioquest | 1 mg | EUR 176 |
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16892 | AAT Bioquest | 1 mg | EUR 176 |
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23150 | AAT Bioquest | 300 Tests | EUR 306 |
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23153 | AAT Bioquest | 300 Tests | EUR 306 |
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23158 | AAT Bioquest | 300 Tests | EUR 306 |
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S0005 | Affbiotech | 200ul | EUR 376 |
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S0006 | Affbiotech | 200ul | EUR 376 |
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S0013 | Affbiotech | 200ul | EUR 304 |
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S0014 | Affbiotech | 200ul | EUR 304 |
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S0017 | Affbiotech | 200ul | EUR 304 |
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S0018 | Affbiotech | 200ul | EUR 304 |
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M09406 | BosterBio | 100ug | EUR 565 |
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human. |
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A4-686-C100 | ExBio | 0.1 mg | EUR 269 |
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A4-712-C100 | ExBio | 0.1 mg | EUR 269 |
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A4-730-C100 | ExBio | 0.1 mg | EUR 269 |
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A4-737-C100 | ExBio | 0.1 mg | EUR 269 |
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A6-686-C100 | ExBio | 0.1 mg | EUR 269 |
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A6-712-C100 | ExBio | 0.1 mg | EUR 269 |
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A6-730-C100 | ExBio | 0.1 mg | EUR 269 |
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A6-737-C100 | ExBio | 0.1 mg | EUR 269 |
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Ab8011-001 | GenDepot | 1mg | EUR 334 |
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Ab8032-001 | GenDepot | 0.5mg | EUR 435 |
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43R-ID012AF | Fitzgerald | 300 ug | EUR 410 |
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594) |
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M02316 | BosterBio | 100ug | EUR 580 |
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human. |
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50336 | Alpha Diagnostics | 0.5 ml | EUR 225 |
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50337 | Alpha Diagnostics | 0.5 ml | EUR 225 |
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C4892-1 | ApexBio | 1 mg | EUR 158 |
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism. |
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C4892-10 | ApexBio | 10 mg | EUR 918 |
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism. |
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C4892-5 | ApexBio | 5 mg | EUR 538 |
Description: MCC-555, also known as RWJ-241947, is a novel peroxisome proliferator?activated receptor ? ligand [1]. The PPAR? receptors mainly express in adipose tissue, colon and macrophages involved in regulating fatty acid storage and glucose metabolism. |
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B6377-10 | ApexBio | 10 mg | EUR 144 |
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. |
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B6377-25 | ApexBio | 25 mg | EUR 276 |
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. |
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B6377-50 | ApexBio | 50 mg | EUR 447 |
Description: AG 555 is a potent and selective inhibitor of EGFR with IC50 value of 0.7 ?M. The epidermal growth factor receptor (EGFR) is the cell-surface receptor for epidermal growth factor and plays an important role in tumor invasion and cancer cell proliferation. |
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HY-15336 | MedChemExpress | 10mM/1mL | EUR 126 |
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RP-555 | Alpha Diagnostics | 10 ug | EUR 164 |
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H-8286.0100 | Bachem | 0.1mg | EUR 312 |
Description: Sum Formula: C205H340N60O53+dye |
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H-8286.0500 | Bachem | 0.5mg | EUR 1017 |
Description: Sum Formula: C205H340N60O53+dye |
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1705 | AAT Bioquest | 1 mg | EUR 306 |
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