A rapid, antibiotic susceptibility test for multi-drug resistant, Gram-negative bacterial uropathogens using the biochemical assay, DETECT

The growing prevalence of prolonged spectrum β-lactamases (ESBLs) and plasmid-mediated AmpC (pAmpC) β-lactamases amongst Enterobacterales threatens our capacity to deal with urinary tract infections (UTIs). These organisms are immune to most β-lactam antibiotics and are regularly multidrug-resistant (MDR).
Consequently, they’re usually immune to antibiotics used to empirically deal with UTIs. The lack of fast diagnostic and antibiotic susceptibility exams (AST) makes medical administration of UTIs brought on by such organisms tough, as normal tradition and susceptibility assays require a number of days. We have tailored a biochemical detection assay, termed dual-enzyme trigger-enabled cascade know-how (DETECT) for fast detection of resistance (time-to-result of three h) to different antibiotics generally utilized in therapy of UTIs.
DETECT is activated by the presence of CTX-M and pAmpC β-lactamases. In this proof-of-concept research, the tailored DETECT assay (AST-DETECT) has been carried out on pure-cultures of Klebsiella pneumoniae and Escherichia coli (48 isolates) expressing ESBL or pAmpC β-lactamases to carry out AST for ciprofloxacin (sensitivity 96.9%, specificity 100%, accuracy 97.9%) nitrofurantoin (sensitivity 95.7%, specificity 91.7%, accuracy 94%) and trimethoprim/sulfamethoxazole (sensitivity 83.3%, specificity 100%, accuracy 89.4%). These outcomes recommend that AST-DETECT could also be tailored as a possible diagnostic platform to quickly detect multidrug-resistant E. coli and Ok. pneumoniae that trigger UTI.
A simplified aortic ring assay: A helpful ex vivo methodology to evaluate biochemical and useful parameters of angiogenesis
We current a simplified methodology for conducting aortic ring assays which yields sturdy sprouting and excessive reproducibility focused in the direction of matrix biologists learning angiogenesis and extracellular matrix signaling. Main changes from beforehand established protocols embrace embedding aortic rings between two layers of 3D kind I collagen matrix and supplementing with vascular endothelial media.
We additionally introduce a concise and efficient staining protocol for acquiring high-resolution photos of intracellular and extracellular matrix proteins together with a extra correct protocol to quantify angiogenesis. Importantly, we current a novel methodology to carry out biochemical analyses of vessel sprouting with out contamination from the aortic ring itself. Overall, our refined methodology permits detection of low abundance and phosphorylated proteins and offers an easy ex vivo angiogenic assay that may be simply reproduced by these in the matrix biology area.

High throughput mechanobiology: Force modulation of ensemble biochemical and cell-based assays
Mechanobiology is concentrated on how the bodily forces and mechanical properties of proteins, cells and tissues contribute to physiology and illness. While the response of proteins and cells to mechanical stimuli is vital for perform, the instruments to probe these actions are sometimes restricted to single molecule manipulations.
Here, we have now developed a novel microplate reader assay to embody mechanical measurements with ensemble biochemical and mobile assays, using a microplate lid modified with magnets. This configuration permits a number of static magnetic tweezers to perform concurrently throughout the microplate, thereby vastly growing throughput.
We show the broad applicability and flexibility by in vitro and in cellulo approaches. Overall, our methodology permits, for the first-time, ensemble biochemical and cell-based assays to be carried out beneath drive, in excessive throughput format. This method considerably will increase the availability of mechanobiology measurements.
Biomonitoring findings for occupational lead publicity in battery and ceramic tile employees using biochemical markers, alkaline comet assay, and micronucleus test coupled with fluorescence in situ hybridisation
Manufacture of lead-containing merchandise has lengthy been related to varied well being dangers. To get an perception into the associated genotoxic dangers, we performed a biomonitoring research in 50 uncovered employees and 48 matched controls using a battery of endpoints that sensitively detect the extent of genome instability in peripheral blood lymphocytes. The ranges of major DNA injury had been estimated with the alkaline comet assay, whereas cytogenetic abnormalities had been decided with the cytokinesis-block micronucleus (CBMN) cytome assay.
Additionally, CBMN slides of 20 uncovered and 16 management individuals had been subjected to fluorescence in situ hybridisation (FISH), coupled with pancentromeric probes to determine the incidence of centromere-positive micronuclei, nuclear buds, and nucleoplasmic bridges. Blood lead ranges (B-Pb) had been measured with atomic absorption spectrometry.
To additional characterise cumulative results of occupational publicity, we measured erythrocyte protoporphyrin (EP) concentrations and delta-aminolevulinic acid dehydratase (ALAD) exercise in blood. We additionally assessed the affect of serum folate (S-folate) and vitamin B12 (S-B12) on genome stability.
Compared to controls, occupationally uncovered employees demonstrated considerably larger B-Pb (298.36±162.07 vs 41.58±23.02), MN frequency (18.71±11.06 vs 8.98±7.50), centromere optimistic MN (C+ MN) (8.15±1.Eight vs 3.69±0.47), and centromere detrimental MN (C- MN) (14.55±1.80 vs 4.56±0.89). Exposed ladies had considerably larger comet tail depth (TI) and size (TL) than management ladies.
Furthermore, employees confirmed a optimistic correlation between age and nuclear buds and MN, between MN and years of publicity, and between S-B12 ranges and TI and ALAD exercise, whereas a detrimental correlation was discovered between TI and B-Pb. These findings recommend that occupational settings in the manufacture of lead-containing merchandise pose important genotoxic dangers, which calls for creating simpler work security programmes, together with periodical monitoring of B-Pb and genetic endpoints.
Comprehensive bioanalytical multi-imaging by planar chromatography in situ mixed with organic and biochemical assays highlights bioactive fatty acids in abelmosk
The identification of the bioactivity of particular person compounds in pure merchandise is useful to know their therapeutic functions. Thus, a bioanalytical multi-imaging screening was developed and utilized to 54 bark, leaf and seed extracts of Sri Lankan Abelmoschus moschatus (abelmosk) to seek out out the most bioactive particular person compounds. The focus was laid on a complete bioactivity profiling of its extracts.
High-performance thin-layer chromatography (HPTLC) was hyphenated with seven effect-directed assays (EDA), i. e. organic (Gram-negative Aliivibrio fischeri and Gram-positive Bacillus subtilis), biochemical (α-glucosidase, β-glucosidase, acetylcholinesterase and tyrosinase) and chemical (2,2-diphenyl-1-picrylhydrazyl) assays.
This multi-imaging was complemented by ultraviolet (UV), white mild (Vis), fluorescence detection (FLD) and eight microchemical derivatizations. Heated electrospray ionization high-resolution mass spectrometry (HESI-HRMS) was used to characterize the most distinguished multi-potent compound zone. It consisted of coeluting unsaturated fatty acids (linoleic acid and oleic acid), but in addition saturated fatty acids (palmitic acid and to a decrease extent stearic acid, arachidic acid and behenic acid).
For affirmation of the detected results (antibacterial, free radical scavenger and inhibitor of α-glucosidase, β-glucosidase, acetylcholinesterase and tyrosinase), oleic acid was exemplarily analyzed by co-development and overlapped software (with pattern).
![]() Rat Apolipoprotein E (Apo E) ELISA Kit |
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NSL1593r | Sunlong | 96 Tests | 498 EUR |
![]() Goat Apolipoprotein E(Apo E) ELISA Kit |
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NSL1036Gt | Sunlong | 96T | 528 EUR |
![]() Human Apolipoprotein E/Apo E ELISA Kit |
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E28L0615 | EnoGene | 96T | 666.67 EUR |
![]() Human Apolipoprotein E (Apo E) ELISA Kit |
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NSL0134Hu | Sunlong | 96 wells | 468 EUR |
![]() Human Apolipoprotein E(Apo E) ELISA Kit |
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NSL0858Hu | Sunlong | 96 wells | 468 EUR |
![]() Mouse Apolipoprotein E(Apo E) ELISA Kit |
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NSL0955m | Sunlong | 96 Test | 528 EUR |
![]() Mouse Apolipoprotein E (Apo E) ELISA Kit |
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NSL1766m | Sunlong | 96 Test | 528 EUR |
![]() Canine Apolipoprotein E(Apo E) ELISA Kit |
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NSL1798Ca | Sunlong | 1893 wells | 528 EUR |
![]() Bovine Apolipoprotein E(Apo E) ELISA Kit |
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NSL1972Bo | Sunlong | 96 T | 528 EUR |
![]() Cytochalasin E |
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C197-1MG | TOKU-E | 1 mg | 157.2 EUR |
![]() Cytochalasin E |
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C197-5MG | TOKU-E | 5 mg | 462 EUR |
![]() Deoxybrevianamide E |
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D083-1MG | TOKU-E | 1 mg | 333.6 EUR |
![]() Deoxybrevianamide E |
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D083-5MG | TOKU-E | 5 mg | 1076.4 EUR |
![]() Oligomycin E |
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O021-1MG | TOKU-E | 1 mg | 381.6 EUR |
![]() Oligomycin E |
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O021-5MG | TOKU-E | 5 mg | 1248 EUR |
![]() Paraherquamide E |
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P070-0.5MG | TOKU-E | 0.5 mg | 480 EUR |
![]() Paraherquamide E |
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P070-2.5MG | TOKU-E | 2.5 mg | 1590 EUR |
![]() Phenelfamycin E |
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P078-1MG | TOKU-E | 1 mg | 381.6 EUR |
![]() Phenelfamycin E |
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P078-5MG | TOKU-E | 5 mg | 1248 EUR |
![]() Roquefortine E |
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R035-1MG | TOKU-E | 1 mg | 268.8 EUR |
![]() Roquefortine E |
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R035-5MG | TOKU-E | 5 mg | 849.6 EUR |
![]() Berkeleylactone E |
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B087-1MG | TOKU-E | 1 mg | 142.63 EUR |
Description: C20H32O7 |
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![]() Berkeleylactone E |
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B087-5MG | TOKU-E | 5 mg | 498.97 EUR |
Description: C20H32O7 |
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![]() Chevalone E |
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C257-0.5MG | TOKU-E | 0.5 mg | 150.43 EUR |
Description: C20H24O4 |
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![]() Chevalone E |
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C257-2.5MG | TOKU-E | 2.5 mg | 525.85 EUR |
Description: C20H24O4 |
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![]() Chicken Apolipoprotein E(Apo E) ELISA Kit |
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NSL1068Ch | Sunlong | 1163 T | 528 EUR |
![]() Porcine Apolipoprotein E(Apo E) ELISA Kit |
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NSL0871Po | Sunlong | 96T | 528 EUR |
![]() Rat apolipoprotein E (Apo-E) ELISA Kit |
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CSB-E09749r-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
Description: Quantitative competitive ELISA kit for measuring Rat apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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![]() Rat apolipoprotein E (Apo-E) ELISA Kit |
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1-CSB-E09749r | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Rat apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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![]() Rat Apolipoprotein E,Apo-E ELISA Kit |
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CN-01662R1 | ChemNorm | 96T | 549.6 EUR |
![]() Rat Apolipoprotein E,Apo-E ELISA Kit |
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CN-01662R2 | ChemNorm | 48T | 368.4 EUR |
![]() Pig apolipoprotein E (Apo-E) ELISA Kit |
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CSB-E17889p-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
Description: Quantitative competitive ELISA kit for measuring Pig apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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![]() Pig apolipoprotein E (Apo-E) ELISA Kit |
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1-CSB-E17889p | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Pig apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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![]() Rat Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E0753RT-48T | GenAsia Biotech | 48T | 380.4 EUR |
![]() Rat Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E0753RT-96T | GenAsia Biotech | 96T | 595.2 EUR |
![]() Rat Apolipoprotein E(Apo-E)ELISA Kit |
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QY-E10899 | Qayee Biotechnology | 96T | 433.2 EUR |
![]() Rat apolipoprotein E (Apo-E) ELISA Kit |
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EKC40682-48T | Biomatik Corporation | 48T | 374.22 EUR |
![]() Rat apolipoprotein E (Apo-E) ELISA Kit |
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EKC40682-5x96T | Biomatik Corporation | 5x96T | 2539.35 EUR |
![]() Rat apolipoprotein E (Apo-E) ELISA Kit |
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EKC40682-96T | Biomatik Corporation | 96T | 534.6 EUR |
![]() Pig apolipoprotein E (Apo-E) ELISA Kit |
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EKC31444-48T | Biomatik Corporation | 48T | 374.22 EUR |
![]() Pig apolipoprotein E (Apo-E) ELISA Kit |
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EKC31444-5x96T | Biomatik Corporation | 5x96T | 2539.35 EUR |
![]() Pig apolipoprotein E (Apo-E) ELISA Kit |
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EKC31444-96T | Biomatik Corporation | 96T | 534.6 EUR |
![]() Rat Apolipoprotein E,Apo-E ELISA Kit |
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YLA0187RA-48T | Shanghai YL Biotech | 48T | 465 EUR |
![]() Rat Apolipoprotein E,Apo-E ELISA Kit |
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YLA0187RA-96T | Shanghai YL Biotech | 96T | 600 EUR |
![]() Rat Apolipoprotein E,Apo-E ELISA Kit |
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SL0088Ra | Sunlong | - | 498 EUR |
![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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201-12-1452 | SunredBio | 96 tests | 528 EUR |
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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![]() Human apolipoprotein E (Apo-E) ELISA Kit |
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CSB-E09748h-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
Description: Quantitative competitive ELISA kit for measuring Human apolipoprotein E (Apo-E) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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![]() Human apolipoprotein E (Apo-E) ELISA Kit |
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1-CSB-E09748h | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Human apolipoprotein E (Apo-E) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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![]() Mouse apolipoprotein E (Apo-E) ELISA Kit |
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CSB-E09750m-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
Description: Quantitative competitive ELISA kit for measuring Mouse apolipoprotein E (Apo-E) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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![]() Mouse apolipoprotein E (Apo-E) ELISA Kit |
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1-CSB-E09750m | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Mouse apolipoprotein E (Apo-E) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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![]() Mouse Apolipoprotein E,Apo-E ELISA Kit |
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CN-02533M1 | ChemNorm | 96T | 536.4 EUR |
![]() Mouse Apolipoprotein E,Apo-E ELISA Kit |
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CN-02533M2 | ChemNorm | 48T | 355.2 EUR |
![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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CN-04043H1 | ChemNorm | 96T | 529.2 EUR |
![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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CN-04043H2 | ChemNorm | 48T | 349.2 EUR |
![]() Human Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E1468HM-48T | GenAsia Biotech | 48T | 346.8 EUR |
![]() Human Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E1468HM-96T | GenAsia Biotech | 96T | 559.2 EUR |
![]() Mouse Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E0145MS-48T | GenAsia Biotech | 48T | 403.2 EUR |
![]() Mouse Apolipoprotein E(Apo-E)ELISA Kit |
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GA-E0145MS-96T | GenAsia Biotech | 96T | 640.8 EUR |
![]() Mouse APO-E(Apolipoprotein E) ELISA Kit |
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EM0846 | FN Test | 96T | 571.5 EUR |
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.938 ng/ml |
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![]() Mouse Apolipoprotein E(Apo-E)ELISA Kit |
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QY-E20152 | Qayee Biotechnology | 96T | 433.2 EUR |
![]() Human Apolipoprotein E(Apo-E)ELISA Kit |
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QY-E00325 | Qayee Biotechnology | 96T | 433.2 EUR |
![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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YLA0887HU-48T | Shanghai YL Biotech | 48T | 435 EUR |
![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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YLA0887HU-96T | Shanghai YL Biotech | 96T | 562.5 EUR |
![]() Human apolipoprotein E (Apo-E) ELISA Kit |
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EKC40681-48T | Biomatik Corporation | 48T | 374.22 EUR |
![]() Human apolipoprotein E (Apo-E) ELISA Kit |
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EKC40681-5x96T | Biomatik Corporation | 5x96T | 2539.35 EUR |
![]() Human apolipoprotein E (Apo-E) ELISA Kit |
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EKC40681-96T | Biomatik Corporation | 96T | 534.6 EUR |
![]() Mouse apolipoprotein E (Apo-E) ELISA Kit |
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EKC40683-48T | Biomatik Corporation | 48T | 374.22 EUR |
![]() Mouse apolipoprotein E (Apo-E) ELISA Kit |
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EKC40683-5x96T | Biomatik Corporation | 5x96T | 2539.35 EUR |
![]() Mouse apolipoprotein E (Apo-E) ELISA Kit |
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EKC40683-96T | Biomatik Corporation | 96T | 534.6 EUR |
![]() Mouse Apolipoprotein E,Apo-E ELISA Kit |
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YLA0562MO-48T | Shanghai YL Biotech | 48T | 465 EUR |
![]() Mouse Apolipoprotein E,Apo-E ELISA Kit |
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YLA0562MO-96T | Shanghai YL Biotech | 96T | 600 EUR |
![]() Human Apolipoprotein E (Apo-E) ELISA Kit |
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IHUAPOEKT | Innovative research | each | 702 EUR |
Description: Human Apolipoprotein E (Apo-E) ELISA Kit |
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![]() Human Apolipoprotein E,Apo-E ELISA Kit |
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SL0283Hu | Sunlong | 96 Tests | 468 EUR |
![]() Mouse Apolipoprotein E,Apo-E ELISA Kit |
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SL0075Mo | Sunlong | - | 528 EUR |
![]() Rabbit apolipoprotein E (Apo-E) ELISA Kit |
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CSB-E09806Rb-24T | Cusabio | 1 plate of 24 wells | 198 EUR |
Description: Quantitative competitive ELISA kit for measuring Rabbit apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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![]() Rabbit apolipoprotein E (Apo-E) ELISA Kit |
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1-CSB-E09806Rb | Cusabio |
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Description: Quantitative competitive ELISA kit for measuring Rabbit apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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CN-00593R1 | ChemNorm | 96T | 529.2 EUR |
![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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CN-00593R2 | ChemNorm | 48T | 349.2 EUR |
![]() Bovine Apolipoprotein E(Apo-E) ELISA Kit |
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GA-E0027BV-48T | GenAsia Biotech | 48T | 403.2 EUR |
![]() Bovine Apolipoprotein E(Apo-E) ELISA Kit |
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GA-E0027BV-96T | GenAsia Biotech | 96T | 640.8 EUR |
![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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GA-E0037RB-48T | GenAsia Biotech | 48T | 391.2 EUR |
![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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GA-E0037RB-96T | GenAsia Biotech | 96T | 628.8 EUR |
![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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QY-E30266 | Qayee Biotechnology | 96T | 448.8 EUR |
![]() Rabbit Apolipoprotein E,Apo-E ELISA Kit |
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SL0036Rb | Sunlong | - | 498 EUR |
![]() Guinea pig Apolipoprotein E(Apo E) ELISA Kit |
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NSL1107Gp | Sunlong | 96T | 528 EUR |
![]() APO-E ELISA Kit| Mouse Apolipoprotein E ELISA Kit |
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EF013448 | Lifescience Market | 96 Tests | 826.8 EUR |
![]() ELISA kit for Human apolipoprotein E (Apo-E) |
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EK0173 | SAB | 96 tests | 794.4 EUR |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates and other biological fluids. |
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![]() ELISA kit for Mouse apolipoprotein E (Apo-E) |
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EK0321 | SAB | 96 tests | 794.4 EUR |
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse apolipoprotein E (Apo-E) in samples from serum, plasma, tissue homogenates and other biological fluids. |
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![]() *Human Total Apolipoprotein E (Apo-E) ELISA Kit |
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IHUAPOEKTT | Innovative research | each | 528 EUR |
Description: *Human Total Apolipoprotein E (Apo-E) ELISA Kit |
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![]() Human Apolipoprotein E (Apo E) AssayMax ELISA Kit |
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EA8003-1 | AssayPro | 96 Well Plate | 475.2 EUR |
![]() Azithromycin impurity E EvoPure® |
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A074-5MG | TOKU-E | 5 mg | 835.2 EUR |
![]() Apolipoprotein E/Apo-E/APOE |
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E21-J05 | EnoGene | 10ug | 411.6 EUR |
![]() Human apoprotein E 4(apo-E4) ELISA Kit |
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QY-E05660 | Qayee Biotechnology | 96T | 433.2 EUR |
![]() Apo E Protein |
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abx069753-005mg | Abbexa | 0.05 mg | 560.4 EUR |
![]() APO-E Peptide |
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7333P | ProSci | 0.05 mg | 197.7 EUR |
Description: (CT) APO-E Peptide |
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![]() APO-E Antibody |
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7333-002mg | ProSci | 0.02 mg | 206.18 EUR |
Description: APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
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![]() APO-E Antibody |
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7333-01mg | ProSci | 0.1 mg | 523.7 EUR |
Description: APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
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![]() Apolipoprotein E (Apo E) Antibody |
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abx023252-10ml | Abbexa | 10 ml | 510 EUR |
![]() Apolipoprotein E (Apo E) Antibody |
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abx023254-1mg | Abbexa | 1 mg | 644.4 EUR |
![]() Apolipoprotein E (Apo E) Antibody |
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abx023256-1mg | Abbexa | 1 mg | 961.2 EUR |
![]() Apolipoprotein E (Apo E) Antibody |
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abx023258-1ml | Abbexa | 1 ml | 493.2 EUR |
![]() Apolipoprotein E (Apo E) Antibody |
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abx023259-1ml | Abbexa | 1 ml | 627.6 EUR |
![]() Apolipoprotein E (Apo E) Antibody |
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abx024162-10mg | Abbexa | 10 mg | 910.8 EUR |
![]() Human Apolipoprotein E (Apo E) AssayMax ELISA Kit (Positive Control included) |
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EA8003-7 | AssayPro | 96 Well Plate | 546 EUR |
![]() apo-A1/ Rat apo- A1 ELISA Kit |
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ELA-E0604r | Lifescience Market | 96 Tests | 1063.2 EUR |
![]() Apo-E4/ Rat Apo- E4 ELISA Kit |
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ELA-E1858r | Lifescience Market | 96 Tests | 1063.2 EUR |
![]() Apolipoprotein E (Apo E) Antibody (HRP) |
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abx415078-01mg | Abbexa | 0.1 mg | 610.8 EUR |
![]() Apolipoprotein E (Apo E) VLDL Antibody |
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abx024092-1ml | Abbexa | 1 ml | 1178.4 EUR |
![]() Apolipoprotein E (Apo E) Antibody (Biotin) |
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abx415075-01mg | Abbexa | 0.1 mg | 610.8 EUR |
![]() Necrosis vs Apoptosis Kits |
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KF17371 | Neuromics | 50-100 Tests | 522 EUR |
![]() Necrosis vs Apoptosis Kits |
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KF17372 | Neuromics | 100-200 Tests | 921.6 EUR |
![]() Mouse Apolipoprotein E (APO-E) CLIA Kit |
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abx196722-96tests | Abbexa | 96 tests | 990 EUR |
![]() Apo E Antibody (HRP) |
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abx023255-05ml | Abbexa | 0.5 ml | 878.4 EUR |
![]() Apo E Antibody (Biotin) |
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abx023257-05ml | Abbexa | 0.5 ml | 878.4 EUR |
![]() apo-B100/ Rat apo- B100 ELISA Kit |
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ELA-E0603r | Lifescience Market | 96 Tests | 1063.2 EUR |
![]() Polyclonal APO-E Antibody |
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APG01931G | Leading Biology | 0.1 mg | 790.8 EUR |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human APO-E . This antibody is tested and proven to work in the following applications: |
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![]() Apoptolidin |
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A130-0.1MG | TOKU-E | 0.1 mg | 381.6 EUR |
![]() Apoptolidin |
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A130-0.5MG | TOKU-E | 0.5 mg | 1248 EUR |
![]() CLIA kit for Mouse APO-E (Apolipoprotein E) |
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E-CL-M0101 | Elabscience Biotech | 1 plate of 96 wells | 700.8 EUR |
Description: A sandwich CLIA kit for quantitative measurement of Mouse APO-E (Apolipoprotein E) in samples from Serum, Plasma, Cell supernatant |
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![]() Nori® Equine 6-Plex ELISA Kits-BMP |
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GR225025 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-CCL |
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GR225026 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-MMP |
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GR225027 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-TLR |
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GR225028 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-SAA |
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GR225030 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-BMP |
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GR226025 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-CCL |
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GR226026 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-MMP |
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GR226027 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-TLR |
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GR226028 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-SAA |
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GR226030 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-BMP |
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GR228025 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-CCL |
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GR228026 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-MMP |
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GR228027 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-TLR |
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GR228028 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-SAA |
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GR228030 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-BMP |
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GR224025 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-CCL |
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GR224026 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-MMP |
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GR224027 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-TLR |
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GR224028 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-SAA |
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GR224030 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-S100 |
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GR225031 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-CXCL |
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GR225032 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-S100 |
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GR226031 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-CXCL |
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GR226032 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-S100 |
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GR228031 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-CXCL |
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GR228032 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-S100 |
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GR224031 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-CXCL |
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GR224032 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-Hormones |
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GR225029 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-Hormones |
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GR226029 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-Hormones |
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GR228029 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-Hormones |
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GR224029 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 3-Plex ELISA Kits-Interferons |
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GR225009 | Genorise Scientific | 96-well | 503 EUR |
![]() Nori® Canine 3-Plex ELISA Kits-Interferons |
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GR226009 | Genorise Scientific | 96-well | 503 EUR |
![]() Nori® Bovine 3-Plex ELISA Kits-Interferons |
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GR228009 | Genorise Scientific | 96-well | 503 EUR |
![]() EdU Imaging Kits (488) |
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K1175-50 | ApexBio | 50-500 tests | 300 EUR |
Description: EdU Imaging Kits (488) is a sensitive and reliable way to detect and quantify cell proliferation in cells. It is optimized for fluorescence microscopy. It is a better alternative to traditional BrdU (bromodeoxyuridine). |
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![]() Nori® Porcine 3-Plex ELISA Kits-Interferons |
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GR224009 | Genorise Scientific | 96-well | 503 EUR |
![]() Nori® Equine 4-Plex ELISA Kits-Immunoglobulins |
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GR225017 | Genorise Scientific | 96-well | 545 EUR |
![]() Nori® Canine 4-Plex ELISA Kits-Immunoglobulins |
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GR226017 | Genorise Scientific | 96-well | 545 EUR |
![]() Nori® Bovine 4-Plex ELISA Kits-Immunoglobulins |
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GR228017 | Genorise Scientific | 96-well | 545 EUR |
![]() Nori® Porcine 4-Plex ELISA Kits-Immunoglobulins |
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GR224017 | Genorise Scientific | 96-well | 545 EUR |
![]() APO E4 ELISA KIT|Human |
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EF001197 | Lifescience Market | 96 Tests | 826.8 EUR |
![]() Human Apo(a) ELISA Kit |
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STA-359 | Cell Biolabs | 96 assays | 866.4 EUR |
Description: Lipoprotein(a), or Lp(a), is a low density lipoprotein (LDL)-like particle synthesized by the liver that consists of ApoB-100 molecule covalently linked to a very large glycoprotein known as apolipoprotein(a) or Apo(a). Cell Biolabs? Human Apo(a) ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of human Apo(a) in plasma, serum or other biological fluid samples. The kit has detection sensitivity limit of 1 ng/mL human Apo(a). Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. |
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![]() Nori® Equine 6-Plex ELISA Kits-Cardiac Panel |
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GR225034 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-Cardiac Panel |
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GR226034 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-Cardiac Panel |
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GR228034 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-Cardiac Panel |
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GR224034 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Equine 6-Plex ELISA Kits-Growth Factors |
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GR225024 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Canine 6-Plex ELISA Kits-Growth Factors |
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GR226024 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Bovine 6-Plex ELISA Kits-Growth Factors |
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GR228024 | Genorise Scientific | 96-well | 629 EUR |
![]() Nori® Porcine 6-Plex ELISA Kits-Growth Factors |
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GR224024 | Genorise Scientific | 96-well | 629 EUR |
The confirmed results underlined the helpful well being results derived from unsaturated fatty acids like oleic acid. Exemplarily, the α-glucosidase and tyrosinase inhibition responses of the multi-potent compound zone had been quantified equivalently in reference to oleic acid. The comparable outcomes obtained by two impartial enzymatic responses efficiently proved the use of biochemical quantification by planar enzyme assays, and thus the new methodology based mostly on HPTLC-UV/Vis/FLD-EDA-HESI-HRMS.
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